跨越时空的细胞地图：Moscot框架助力单细胞基因组学的新革命
近日，来自慕尼黑工业大学、慕尼黑亥姆霍兹大学和苏黎世联邦理工学院的跨学科研究团队发布了一项重要研究，提出了名为 Moscot（多组学单细胞最优传输）的创新框架，成功重建了170万个小鼠胚胎细胞在20个时间点的发育轨迹。这项研究在《Nature》杂志上发表，标志着单细胞基因组学领域的一个重大突破。Moscot 框架的设计灵感源自18世纪的最优传输理论，该理论旨在高效地将物体从一个地方移动到另一个地方。研究人员通过将生物映射和比对任务转化为最优传输问题，并采用一系列一致
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