跨越時空的細胞地圖：Moscot框架助力單細胞基因組學的新革命
近日，來自慕尼黑工業大學、慕尼黑亥姆霍茲大學和蘇黎世聯邦理工學院的跨學科研究團隊發佈了一項重要研究，提出了名爲 Moscot（多組學單細胞最優傳輸）的創新框架，成功重建了170萬個小鼠胚胎細胞在20個時間點的發育軌跡。這項研究在《Nature》雜誌上發表，標誌着單細胞基因組學領域的一個重大突破。Moscot 框架的設計靈感源自18世紀的最優傳輸理論，該理論旨在高效地將物體從一個地方移動到另一個地方。研究人員通過將生物映射和比對任務轉化爲最優傳輸問題，並採用一系列一致
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