Open-LLM-VTuber is an open-source project designed for interaction with large language models (LLMs) via voice, featuring real-time Live2D facial capture and cross-platform long-term memory capabilities. This project supports macOS, Windows, and Linux platforms, allowing users to select different speech recognition and speech synthesis backends, as well as customized long-term memory solutions. It is particularly suited for developers and enthusiasts looking to implement natural language conversations with AI across various platforms.