ReMe is a personalized cognitive training framework jointly developed by Microsoft Research Asia and the Shanghai Mental Health Center, designed to provide personalized cognitive training for patients with cognitive impairments. This framework is based on Microsoft Azure's OpenAI services, utilizing multimodal large model technology to provide users with cognitive training experiences through various input and output modes, including text, images, and voice, in the form of a conversational agent. The innovation of ReMe lies in its ability to provide personalized and multimodal interaction capabilities, offering tailored training programs based on users' memory content and cognitive levels, thereby enhancing the relevance and effectiveness of training.